The nucleus can be viewed using a special technique in microscopy. Use of this method allows us to avoid the nucleus during the ICSI procedure where the pipette containing sperm is injected into the sperm. Considering that mitotic spindles cover an area that is roughly 1/200 of the entire ooplasm, the chances of disrupting the spindles and thus reducing pregnancy rate are rather low. This method is more useful in a research environment. Research shows that this technique does not have a direct effect on increasing pregnancy rate.
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